Factors affecting the speed of agglutination in the Coombs test.

نویسنده

  • I D P WOOTTON
چکیده

The Coombs test (Coombs, Mourant, and Race, 1945a, 1945b, 1946) has become popular as a sensitive and reliable method of detecting incomplete antibodies. The essential reagent is the serum of an animal (usually a rabbit) which has been immunized with human globulin. Potent rabbit sera sometimes show a prozone phenomenon (Wootton, 1950; Van Loghem, Kresner, Coombs, and Fulton Roberts, 1950). The experiments described here give details of this phenomenon, and provide information on the conditions necessary for maximum sensitivity in the Coombs test.

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عنوان ژورنال:
  • Journal of clinical pathology

دوره 4 3  شماره 

صفحات  -

تاریخ انتشار 1951